Dermaduction is a transdermal delivery system that employs microscopic channels in the skin’s surface to enhance the penetration and absorption of active ingredients into the dermis. The process creates temporary microperforations in the stratum corneum without causing permanent damage to the skin barrier function.
The technique utilizes precision-engineered microstructures that generate controlled microscopic pathways through the epidermis. These pathways facilitate enhanced bioavailability of topically applied substances, bypassing the skin’s natural barrier mechanisms. The depth and pattern of these microchannels are calibrated to optimize therapeutic agent delivery while maintaining skin integrity.
This method achieves superior penetration rates compared to traditional topical applications, with documented increases in active ingredient absorption of up to 300%. The temporary nature of the microchannels allows for rapid healing, typically within 24 hours, while the enhanced delivery window enables efficient transdermal drug administration. Applications include pharmaceutical delivery, cosmeceutical treatments, and dermatological therapies.
