Dermainduction is a therapeutic skin treatment process that creates controlled micro-injuries in the dermis layer to stimulate natural healing mechanisms and collagen production. The procedure utilizes precise mechanical or electrical instruments to penetrate the skin at specific depths, triggering cellular regeneration and enhanced dermal remodeling.

The technique activates fibroblast proliferation through mechanical transduction, initiating a cascade of healing responses including platelet-derived growth factor release and neovascularization. This controlled trauma induces the synthesis of type I and III collagen, elastin, and glycosaminoglycans within the extracellular matrix.

Clinical applications include scar reduction, wrinkle diminishment, and skin texture improvement. The depth of penetration ranges from 0.25mm to 2.5mm, depending on the treatment area and desired outcome. The process generates new tissue formation through upregulation of transforming growth factor-β, vascular endothelial growth factor, and epidermal growth factor, resulting in enhanced skin structure and function.