Microfenestration is a surgical technique involving the creation of microscopic openings or windows in biological tissue or medical implants, typically measuring between 1 and 100 micrometers in diameter. This precise procedure enhances fluid exchange, cellular migration, and tissue integration at the microscopic level.
The process employs specialized laser systems or mechanical micro-drilling techniques operating at submillimeter precision. These engineered micropores facilitate controlled substance delivery, tissue regeneration, and improved biological interface interactions. The size, pattern, and density of these microscopic fenestrations directly influence their functional efficacy.
Medical applications include ophthalmological implants, drug-delivery systems, and tissue engineering scaffolds. The technique has revolutionized glaucoma treatment through micro-fenestrated shunts and enhanced corneal healing through strategic microperforation patterns. Recent developments incorporate smart materials that respond to physiological conditions, allowing dynamic control of the fenestration apertures.
